Description
DUROLANE 60mg / 3ml – Single-Injection Hyaluronic Acid Viscosupplement
DUROLANE 60mg / 3ml NASHA Technology Joint Injection by Bioventus for Knee, Hip & Multi-Joint Osteoarthritis Pain Relief
Product Overview of DUROLANE 60mg / 3ml
DUROLANE 60mg / 3ml is a Class III medical device manufactured by Bioventus (originally developed by Q-Med), designed to relieve pain caused by osteoarthritis through a single intra-articular injection. Unlike many viscosupplements that require a series of three to five injections, DUROLANE delivers its full dose in one visit, making it a convenient, minimally invasive option for patients whose osteoarthritis pain hasn’t responded adequately to simple analgesics like acetaminophen or conservative non-pharmacological therapy.
Supplied as a single-use, pre-filled 3ml glass syringe containing 60mg of non-animal stabilized hyaluronic acid (NASHA), DUROLANE is indicated for the symptomatic treatment of mild to moderate osteoarthritis of the knee and hip, as well as the ankles, shoulders, elbows, wrists, fingers, and toes.
Key Features of DUROLANE 60mg / 3ml
- Volume: 1 x 3ml pre-filled glass syringe
- Manufacturer: Bioventus (originally Q-Med AB)
- Active Ingredient: Non-animal stabilized hyaluronic acid (NASHA), 20mg/ml concentration
- Total Dose: 60mg sodium hyaluronate per syringe
- Origin: Bio-synthesized through bacterial fermentation, non-animal origin
- Classification: Class III medical device (CE 2797)
- Formulation: Sterile, viscoelastic, transparent gel in a physiological buffer solution, pH-adjusted to 7
- Administration: Single intra-articular injection
How DUROLANE 60mg / 3ml Works
Sodium hyaluronate is a substance naturally found throughout the body, particularly in joint tissue and the fluid surrounding it. In the knee, hip, and other joints, this naturally occurring linear polymer works as a lubricant and shock absorber. In joints affected by osteoarthritis, both the concentration and the lubricating and cushioning ability of this natural hyaluronate can become diminished.
DUROLANE’s NASHA technology stabilizes naturally entangled hyaluronic acid chains, giving the product the highest reported molecular weight among comparable HA products. Because of this high concentration and stabilization, DUROLANE breaks down in the body more gradually than many other hyaluronic acid products, injected directly into the affected joint to improve lubrication and cushioning, thereby reducing pain associated with movement. Since the hyaluronic acid is produced through bacterial fermentation rather than an animal source, DUROLANE is free of irritants or contaminants and is not known to cause immunogenic reactions.
Benefits
- Relieves knee, hip, and other joint pain from osteoarthritis
- Provides lubrication and cushioning to the affected joint
- Requires only a single injection, unlike multi-dose viscosupplement regimens
- Minimally invasive with no downtime
- Symptomatic relief reported to last 6 months or more
- May be re-administered as many times as needed over a patient’s lifetime
- Quick in-office procedure, typically taking around 10 minutes
- Special stabilized HA form associated with fewer injection-site side effects than some other types
Indications
DUROLANE is indicated for the symptomatic treatment of:
- Mild to moderate osteoarthritis of the knee and hip
- Mild to moderate osteoarthritis pain of the ankles, shoulders, elbows, wrists, fingers, and toes
- Pain following joint arthroscopy in the presence of osteoarthritis, within three months of surgery
Administration
DUROLANE is administered by a trained healthcare professional as a single intra-articular injection. The skin is cleaned and, if needed, numbed prior to injection; any excess joint fluid is removed beforehand. An appropriately sized needle (typically 18G–22G, depending on joint size) is used, and aseptic technique is maintained throughout to minimize infection risk.
Why Choose DUROLANE?
- Single-injection convenience: One dose delivers extended symptom relief, unlike multi-injection viscosupplement courses
- High molecular weight: NASHA technology gives DUROLANE the greatest reported molecular weight among comparable HA products, supporting gradual, sustained breakdown
- Trusted manufacturer: Produced by Bioventus, with a formulation used in over 4.5 million NASHA-based injections
- Broad joint coverage: Approved for use in the knee, hip, and several smaller joints
- FDA-approved: Extensively studied in clinical trials for safety and efficacy
- Minimal side effects: Non-animal origin and high purity support a favorable tolerability profile
Important Usage Notes
DUROLANE is intended strictly for administration by an authorized physician, injected directly into the joint using aseptic technique. It is for single use only. As with any intra-articular injection, mild and temporary side effects at the injection site may occur. Product information is provided for professional and patient reference only and is not intended to replace medical advice from a licensed healthcare provider.
