Description
Guna Medical Devices MD-TISSUE 10vials 2ml – Collagen Medical Device for Skin & Connective Tissue Regeneration
Guna Medical Devices MD-TISSUE 10vials 2ml Porcine Collagen Injectable by Guna for Facial Revitalization, Tendon Support & Tissue Repair
Product Overview of Guna Medical Devices MD-TISSUE 10vials 2ml
Guna Medical Devices MD-TISSUE 10vials 2ml is an injectable collagen medical device manufactured by Guna S.p.A. in Italy, developed to support and restore the trophism of connective tissue, particularly within the extracellular matrix. Designed for use by both women and men, MD-TISSUE combines purified porcine-derived collagen with a blend of vitamins and minerals, offering a dual-purpose treatment applicable to both aesthetic facial revitalization and musculoskeletal support for tendons, ligaments, and joints.
Supplied as a box of 10 sterile, pyrogen-free vials of 2ml each, MD-TISSUE ensures a controlled dose and ease of handling during professional treatment sessions.
Key Features pf Guna Medical Devices MD-TISSUE 10vials 2ml
- Volume: 10 vials x 2ml (extraction volume)
- Manufacturer: Guna S.p.A., Milan, Italy
- Formulation: Collagen of porcine origin, ascorbic acid (vitamin C), magnesium gluconate, pyridoxine hydrochloride (vitamin B6), riboflavin (vitamin B2), thiamine hydrochloride (vitamin B1), NaCl, water for injection
- Collagen Content: 100 micrograms per 2ml vial
- Sterility: Sterile, isotonic, pyrogen-free solution
- Administration Routes: Periarticular, peritendinous, intramuscular, and intradermal injection
- Suggested Needle: 26G x 13mm for periarticular use
How Guna MD-TISSUE Works
MD-TISSUE’s purified and titrated porcine-derived hydrolyzed collagen acts as an essential structural element for the regeneration and strengthening of connective tissue. When administered locally, it encourages the body’s own endogenous biosynthesis of new collagen — a key step in skin repair, joint support, and the restoration of dermal support structures.
In aesthetic applications, the collagen intensively moisturizes mature skin and mechanically remodels tissue, reducing the appearance of wrinkles and other symptoms of skin aging, including photoaging. In musculoskeletal applications, collagen administered by periarticular, intraarticular, intramuscular, or intradermal injection provides mechanical support, with a positive effect on joint hypermobility stabilization, movement, pain, and quality of life. The formula’s added vitamins and minerals serve as ancillary components that support better, more targeted positioning of the collagen in situ, helping create a defense barrier against free radicals and counteract the physiological aging of connective tissue.
Benefits
- Intensively moisturizes mature skin and reduces wrinkles and photoaging symptoms
- Mechanically remodels tissue and smooths skin texture
- Supports the regeneration and functional recovery of connective tissues, including tendons and ligaments
- Reduces pain and improves mobility in affected joints and tissues
- Restores elasticity in aging or overused tissue
- Can be used alone or alongside other aesthetic treatments such as hyaluronic acid or botulinum toxin
- Results are evident from around the third week of treatment
- Natural-looking outcomes with gradual improvement in skin quality, texture, and firmness
Common Treatment Areas & Indications
Guna MD-TISSUE is commonly used for:
Aesthetic applications:
- Facial revitalization and biolifting
- Wrinkle reduction and mature skin hydration
- Photoaging correction
Musculoskeletal applications:
- Tendinopathies (epicondylitis, Achilles tendonitis, supraspinatus tendonitis)
- Connective tissue disorders (plantar fasciitis)
- Scars and wound support
- Joint stiffness and overuse injuries
Treatment Protocol
For musculoskeletal use, 1–2 infiltrations per week are typically administered to contain the physiological deterioration of soft tissues (tendons, ligaments, joint capsule). Results are generally evident from the third week, and depending on the patient’s clinical situation, treatment can continue up to the tenth week without added risk. Protocols may vary depending on whether the treatment is aesthetic or musculoskeletal in focus.
Why Choose Guna MD-TISSUE?
- Dual-purpose formula: Effective for both aesthetic skin revitalization and musculoskeletal tissue support
- Trusted Italian manufacturer: Produced by Guna S.p.A., a company specializing in collagen-based medical devices
- Multi-vitamin enriched: Added vitamin C, B1, B2, B6, and magnesium support targeted collagen positioning
- Versatile administration: Suitable for periarticular, peritendinous, intramuscular, and intradermal injection
- Combinable treatment: Can be used as a standalone treatment or alongside hyaluronic acid or botulinum toxin
- Clinically studied: Supported by published case studies and clinical investigations across tendinopathy and skin revitalization applications
Important Usage Notes
Guna MD-TISSUE should be administered by licensed healthcare practitioners only, under medical supervision. It should not be injected in cases of known allergy to any of its components, particularly to animal-derived (porcine) collagen. It is also contraindicated in individuals with uncontrolled local or systemic infections. Product information is provided for professional and clinical reference only and is not intended to diagnose, treat, cure, or prevent any medical condition.
