Description
SKIN-OX (3x5ml)
SKIN-OX (3x5ml) Antioxidant Biorevitalizing Solution for Face, Neck, Décolleté & Hands
SKIN-OX (3x5ml) by Italfarmacia is a Class III medical device designed to fill and remodel the dermal matrix using low-molecular-weight hyaluronic acid combined with a powerful antioxidant complex. Part of the renowned Italfarmacia Skin line, SKIN-OX targets chrono-aging and photodamage at the cellular level, offering practitioners a biorevitalizing treatment that goes beyond simple hydration to actively support skin renewal and brightening.
What Is SKIN-OX (3x5ml)?
SKIN-OX is a filling and modeling solution formulated with fragmented hyaluronic acid (20–38 monomers), amino acids, reduced glutathione, and sodium ascorbyl phosphate in a phosphate-based buffer system. Rather than simply adding volume, SKIN-OX works through the “Skin Improve” technique — a mesotherapy approach designed to optimize skin physiology by activating fibroblasts, stimulating neoformation of matrix components, and normalizing the skin’s colloidal state, while its antioxidant components help protect against oxidative damage from free radicals.
Pack Details
- 3 vials per box, 5ml each
- CE-marked Class III Medical Device, issued by the Higher Institute of Health
- For professional use only — administered exclusively by qualified medical practitioners
Key Ingredients
- Hyaluronic Acid Fragments (20–38 monomers) – low-molecular-weight fragments capable of activating CD44 receptors in fibroblasts, triggering the skin’s own repair and renewal processes
- Amino Acids – precursors of collagen, elastin, and glycosaminoglycans, supplying the raw materials fibroblasts need to rebuild the dermal matrix
- Reduced Glutathione – a potent antioxidant that helps block oxidative damage and supports a brighter, more even skin tone
- Sodium Ascorbyl Phosphate – a stable vitamin C derivative that reinforces antioxidant protection and supports collagen synthesis
- Phosphate-Based Buffer System – helps maintain the sol state of the dermal matrix’s colloidal solution, facilitating better metabolic exchange within the tissue
How SKIN-OX Works
By activating CD44 receptors on fibroblasts, SKIN-OX’s hyaluronic acid fragments encourage the skin to produce its own collagen, elastin, and glycosaminoglycans — the core structural components of youthful, resilient skin. At the same time, its antioxidant components neutralize oxygen free radicals, one of the primary drivers of chrono-aging and photodamage. This dual-action approach supports overall skin quality while helping address the appearance of dark spots and uneven pigmentation caused by melanin accumulation.
Indications & Treatment Areas
SKIN-OX is designed for use on the:
- Face
- Neck
- Décolleté
- Hands
It is commonly used for:
- General skin brightening and radiance
- Photodamage and chronoaging correction
- Skin discoloration and hyperpigmentation
- Overall biorevitalization as a standalone treatment or paired with SKIN-COLIN
Treatment Protocols
- Brightening: one session every 30 days, alone or in combination with Skin-Colin
- Photodamage & chronoaging: one session every 7 days for one month
- Skin discoloration: injected directly onto the affected spot once weekly until the desired lightening effect is achieved
Treatment may be performed at any time of year, though results and duration vary by individual.
Why Practitioners Choose SKIN-OX
- Dual-action formula combining biorevitalization with antioxidant protection
- Backed by Italfarmacia’s established Skin line of dermal matrix treatments
- Flexible protocol suited to brightening, anti-aging, and pigmentation correction
- CE-marked Class III medical device manufactured under strict quality standards
- Can be paired with complementary treatments such as Skin-Colin for enhanced results
- Suitable for multiple body areas beyond the face, including neck, décolleté, and hands
Who Should Use This Product
SKIN-OX is intended strictly for administration by licensed and qualified medical professionals as part of a structured mesotherapy or biorevitalization protocol. Proper patient assessment is recommended prior to treatment to confirm suitability.
Order SKIN-OX (3x5ml) today and offer your patients a clinically formulated, antioxidant-powered solution for brighter, healthier, more revitalized skin.
Medical device for professional use only. Individual results may vary.

